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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : -5 مورد

Antibiotic treatment of Shigella infection in adults

Antibiotic treatment of Shigella infection in adults
Antibiotic Dose Duration*
Levofloxacin 500 mg orally once daily 3 days
Ciprofloxacin 500 mg orally twice daily or 750 mg orally once daily 3 days
Azithromycin 500 mg orally once daily 3 days
Cefixime 200 mg orally twice daily 5 days
Ceftriaxone 1 to 2 g intravenously once daily 5 days
Trimethoprim-sulfamethoxazole (co-trimoxazole) 160/800 mg (one double-strength tablet) orally twice daily 5 days
Ampicillin 500 mg orally every 6 hours 5 days
Selection of antibiotic therapy for Shigella infection in adults should be based on the results of antimicrobial susceptibility testing, if possible. If an agent needs to be chosen empirically, the risk of resistance based on patient demographics and local rates of resistance should be taken into account. Refer to the UpToDate topic on treatment of Shigella infection in adults for additional details.

* For patients with infection due to Shigella dysenteriae type 1 or with HIV coinfection, we treat for 5 to 7 days; in the rare event of bacteremia, we treat for 14 days.

¶ Treatment failures have been reported for cefixime; clinical follow-up is essential.

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