NCI CTCAE v5.0 nausea and vomiting

Adverse event	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Nausea	Loss of appetite without alteration in eating habits	Oral intake decreased without significant weight loss, dehydration, or malnutrition	Inadequate oral caloric or fluid intake; tube feedings, TPN, or hospitalization indicated
Vomiting	Intervention not indicated	Outpatient intravenous hydration; medical intervention indicated	Tube feeding, TPN, or hospitalization indicated	Life-threatening consequences	Death

Nausea is characterized by a queasy sensation and/or the urge to vomit. Vomiting is characterized by the reflexive act of ejecting the contents of the stomach through the mouth.

NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events; TPN: total parenteral nutrition.

Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed March 27, 2018).

Graphic 69015 Version 11.0

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NCI CTCAE v5.0 nausea and vomiting