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Diagnostic tests for Legionella species

Diagnostic tests for Legionella species
Test characteristic  Urine antigen test Culture PCR
Strains detected Detects only L. pneumophila serogroup 1* All species and serogroups All species and serogroups
Time to results <1 hour ≥3 days Hours
Overall sensitivity 70 to 80 percent <10 to 80 percent Exceeds culture
Overall specificity >99 percent 100 percent >99 percent
PCR: polymerase chain reaction.
* L. pneumophila accounts for about 85 percent of cases worldwide but rates may be lower in some regions of the world, such as Australia and New Zealand, where L. longbeachae is prevalent.
¶ Typically detects twice as many cases as culture when testing lower respiratory samples.
Graphic 69022 Version 5.0

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