CLIP (Cancer of the Liver Italian Program) scoring system for hepatocellular cancer

Variable	Score
Child-Pugh stage
A	0
B	1
C	2
Tumor morphology
Uninodular and extension ≤50%	0
Multinodular and extension ≤50%	1
Massive or extension >50%	2
Alpha-fetoprotein
<400	0
≥400	1
Portal vein thrombosis
No	0
Yes	1

The Cancer of the Liver Italian Program (CLIP) score has been used to predict survival in patients with hepatocellular carcinoma. The total score is derived by adding each of the subscores. In one study, median survival was 36, 22, 9, 7, and 3 months for patients in CLIP categories 0, 1, 2, 3, and 4 to 6, respectively.

Graphic 69726 Version 5.0

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CLIP (Cancer of the Liver Italian Program) scoring system for hepatocellular cancer