Plasma cells are identified by their eccentric, clock-face nucleus and pale perinuclear cytoplasmic crescent. They are characteristic of autoimmune hepatitis, but neither pathognomonic of the disease or required for its diagnosis. Staining by hematoxylin-eosin; original magnification x 400.
Reproduced with permission from the American Association for the Study of Liver Diseases. Hepatology 2002; 36:479.
