Light microscopy of glomerulus in scleroderma renal crisis

Light micrograph showing fibrinoid necrosis in the preglomerular afferent arteriole (arrow) in scleroderma renal crisis. The normal muscle layer of the media has been replaced by the fibrinoid material.

Light micrograph of a normal glomerulus. There are only one or two cells per capillary tuft, the capillary lumens are open, the thickness of the glomerular capillary wall (long arrow) is similar to that of the tubular basement membranes (short arrow), and the mesangial cells and mesangial matrix are located in the central or stalk regions of the tuft (arrows).