Significant left ventricular dysfunction predicts stroke in AF

In a prospective study of 1066 patients entered into three clinical trials evaluating the role of anticoagulation in nonvalvular AF (BAATAF, SPINAF, and SPAF), the incidence of a stroke was 9.3 percent per year in patients with moderate to severe left ventricular dysfunction compared with 4.4 percent per year in those with normal or mildly abnormal left ventricular function.