Inflammatory disease | ADEM/MDEM, MOGAD, NMOSD, SLE, PACNS, APS, Sjögren syndrome, Behçet syndrome |
CNS malignancy | Lymphoma, high grade glioma, hemophagocytic lymphohistiocytosis |
Leukodystrophy | Metachromatic leukodystrophy, X-linked adrenoleukodystrophy, Alexander disease |
CNS infection | Acute bacterial or viral infections, Lyme disease, West Nile virus, syphilis, HIV |
Vitamin deficiency | B12, folate |
Granulomatous disease | Neurosarcoidosis, granulomatosis with polyangiitis (Wegener) |
Mitochondrial disease | Leber hereditary optic neuropathy |
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