Topical retinoids for treatment of photoaging^[1]

Topical retinoid	Preparations
Tretinoin	Altreno (0.05% lotion) Atralin^* (0.05% micronized gel) Avita (0.025% cream and gel) Refissa^¶ (0.05% cream) Renova^¶ (0.02% cream) Retin-A (0.025%, 0.05%, 0.1% cream; 0.01%, 0.025% gel) Retin-A Micro (0.04%, 0.06%, 0.08%, and 0.1% microsphere gel) Generic (0.025%, 0.05%, 0.1% cream; 0.01%, 0.025%, 0.04%, 0.05%, 0.1% gel)
Tazarotene	Arazlo (0.045% lotion) Fabior (0.1% foam) Tazorac (0.05%, 0.1% cream and gel) Generic (0.1% cream)
Adapalene (off-label use)	Differin (0.1% cream, gel, and lotion; 0.3% gel) Differin XP (United States: not available) (0.3% gel) Generic (0.1% cream, gel, pad, and solution; 0.3% gel)

Topical retinoid preparations are used off-label for treatment of photoaging, unless otherwise noted. For additional information including doses, administration, and precautions, refer to the topic review of photoaging and drug monographs included within UpToDate.

FDA: US Food and Drug Administration.

* Contains soluble fish proteins and should be used with caution in patients with known sensitivity or allergy to fish.

¶ FDA-approved as adjunctive treatment for palliation of fine wrinkles (Renova, Refissa), mottled hyperpigmentation, and facial skin roughness (Refissa) in patients who use comprehensive skin care and sun avoidance programs.

Reference:

Chien A, Voorhees JJ, King S. Topical retinoids. In: Fitzpatrick's Dermatology in General Medicine, 8th ed, Goldsmith LA, Katz SI, Gilchrest BA (Eds), McGraw-Hill 2012.

Data from: UpToDate Lexidrug. More information available at https://online.lexi.com/.

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Topical retinoids for treatment of photoaging[1]

Topical retinoids for treatment of photoaging^[1]