History |
Onset of symptoms in early infancy |
Neonatal respiratory distress +/- ventilatory support |
Neonatal neurologic dysfunction |
Intractable wheezing unresponsive to bronchodilators |
Wheezing associated with feeding or vomiting |
Difficulty swallowing +/- recurrent vomiting |
Diarrhea |
Poor weight gain |
Stridor |
Oxygen requirement >1 week after acute attack |
Physical examination |
Failure to thrive |
Clubbing |
Cardiac murmur |
Stridor |
Focal lung signs |
Nasal polyps |
Crackles on auscultation |
Cyanosis |
Laboratory features |
Focal or persistent chest radiograph abnormalities |
Anemia |
Irreversible airflow obstruction |
Hypoxemia |
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