Version May 2024
| Scotland (1954-68) | New York (1959-69) | Israel (1973-82) | France (1960-95) | Thailand (1982-92) | Greece (1984-90) | Spain (1988-97) | Singapore (1994-97) | |
| Idiopathic/unknown | 17% | 28% | 32% | 55% | 72% | 35% | 34% | 60% |
| Sarcoidosis | 14% | 24% | 1 patient | 11% | 0% | 28% | 22% | 0% |
| Streptococcal infection | 48% | 14% | 44% | 28% | 6% | 6% | 7% | 9% |
| TB | 20% | 1 patient | 1 patient | 1 patient | 12% | 1.5% | 5% | 3% |
| Infections other than TB or strep¶ | 1 patient | 9% | 0% | 2.5% | 0% | 11% | 22% | 21% |
| Pregnancy or OCAs | 0% | 0% | 10% | 3% | 0%Δ | 10% | 1 patient | 4% |
| Drugs other than OCAs | 0% | 6% | 6% | 0% | 7% | 4% | 2% | 0% |
| Inflammatory bowel disease | 0% | 16% | 1 patient | 1.5% | 0% | 0% | 3% | 0% |
| Behçet syndrome | 0% | 0% | 0% | 0% | 3% | 4% | 2% | 3% |
| Other◊ | 1 patient | 7% | 1 patient | 0% | 0% | 1 patient | 3% | 0% |
TB: tuberculosis; OCA: oral contraceptive.
* These case series involved 136 outpatients in rural Scotland, 57 hospitalized patients in Rochester, New York, 42 inpatients and 8 outpatients at a referral center in Israel, 157 inpatients at a university hospital in Strasbourg, France, 100 hospitalized patients at a university hospital in Bangkok, 45 outpatients and 87 inpatients at a university hospital in Greece, 106 patients at a mixed rural-urban referral center in Spain, and 75 patients seen at the National Skin Center, Singapore.
¶ Other infections included a single case of dermatophytic fungal infection (Scotland); single cases of leprosy, pneumococcal pneumonia, influenza, fungal mycetoma, and gonorrhea (New York); single cases of infection with Yersinia enterocolitica, Mycoplasma pneumoniae, Chlamydia pneumoniae, and Chlamydia trachomatis (France); 21 cases of nonstreptococcal upper respiratory tract infections along with single cases of infection with Brucella abortus and Escherichia coli (Spain); 13 cases of acute infections with Epstein-Barr virus or cytomegalovirus and two cases of salmonellosis (Greece); and 13 cases of viral pharyngitis and single cases of varicella, cat-scratch disease, and gonorrhea (Singapore).
Δ Four patients in this series were taking oral contraceptives, but the authors listed these cases as idiopathic on the basis of durations of administration ranging from two months to eight years prior to the development of erythema nodosum.
◊ Diagnoses listed under "other" included a single case of Hodgkin's disease (Scotland), two systemic lupus erythematosus variants and single cases of pancreatitis and glomerulonephritis (New York), one case of T cell immunodeficiency (Israel), two cases of Sweet's syndrome and one patient with gastric cancer (Spain), and one case of Sjögren's disease (Greece).آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
