Commonly used therapies for myasthenia gravis

	Time to onset of effect^*	Time to maximal effect^*
Symptomatic therapy
Pyridostigmine	10 to 15 minutes	2 hours
Chronic oral immunotherapies
Prednisone	2 to 3 weeks	5 to 6 months
Azathioprine	~12 months	1 to 2 years
Mycophenolate mofetil	6 to 12 months	1 to 2 years
Cyclosporine	~6 months	~7 months
Tacrolimus	~6 months	~12 months
Antibody-based biologic therapies
Fc receptor inhibitors
Efgartigimod alfa	2 to 3 weeks	~4 weeks
Rozanolixizumab	2 to 3 weeks	~4 weeks
Complement inhibitors
Eculizumab	2 to 3 weeks	~4 weeks
Ravulizumab	2 to 3 weeks	~4 to 10 weeks
Zilucoplan	2 to 3 weeks	~4 weeks
B-cell depletion therapy
Rituximab	4 weeks	~8 weeks
Rapid immunotherapies
Plasmapheresis	1 to 7 days	1 to 3 weeks
Intravenous immune globulin	1 to 2 weeks	1 to 3 weeks
Surgery
Thymectomy	1 to 10 years	1 to 10 years

* Estimated times are rough guidelines based upon clinical experience in myasthenia gravis.

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