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Reduction in vertebral fractures with raloxifene

Reduction in vertebral fractures with raloxifene
The cumulative proportion of women with at least one incident VFx at four years. Women with or without prevalent VFxs and who had a baseline and any follow-up radiograph were treated with placebo, or raloxifene 60 mg/day or 120 mg/day.
(A) Total study population (n = 6828).
(B) Women (n = 5077) who reported no use of other bone-active agents in year 4. The numbers above each bar indicate the number of women in each group who had a new VFx.
RR: relative risk; VFx: vertebral fracture.
Reproduced with permission from: Delmas PD, Ensrud KE, Adachi JD, et al. Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis: Four-year results from a randomized clinical trial. J Clin Endocrinol Metab 2002; 87:3609. http://jcem.endojournals.org. Copyright © 2002 The Endocrine Society.
Graphic 70865 Version 9.0

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