Curth's postulates*

Postulates	Definitions
1. Concurrent onset	The dermatosis and malignancy occur concurrently
2. Parallel course	If the malignancy is treated successfully or recurs, the dermatosis follows a similar course
3. Uniformity	A specific malignancy is consistently associated with a specific dermatosis
4. Statistical significance	There is a statistically significant association between the malignancy and the dermatosis based upon case-control studies
5. Genetic basis	There is a genetic association between the malignancy and dermatosis

* Curth's postulates are criteria used to identify a consistent relationship between an internal malignancy and a cutaneous disorder. All criteria do not have to be met.

Adapted from: Thiers BH, Sahn RE, Callen JP. Cutaneous manifestations of internal malignancy. CA Cancer J Clin 2009; 59:73.

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Curth's postulates*