Version May 2024
| Category | Medium | Hysteroscopic procedure | Biochemical properties | Complications or adverse effects | Safety measures[1,2] |
| Gaseous | Carbon dioxide | Diagnostic | Colorless gas | Gas embolism Shoulder pain | Use hysteroscopic insufflator Safety thresholds: Flow <100 mL/min Intrauterine pressure <100 mmHg |
| Electrolyte fluid | Saline 0.9 percent | Diagnostic OR Operative:
| Water and sodium chloride Isotonic | Volume overload | Fluid deficit thresholds: 750 mL: Plan completion of procedure 2500 mL: Stop procedure (or earlier in patients who are elderly or have comorbidities) |
| Lactated Ringer's solution | Diagnostic OR Operative:
| Water and sodium chloride, lactate, potassium, calcium Isotonic | Volume overload | ||
| Electrolyte-poor fluids | Mannitol 5 percent | Operative: monopolar electrocautery only | Six-carbon sugar Cleared by kidneys; acts as its own diuretic Elimination half-life: ≥100 min[3] Isoosmolar | Volume overload Hyponatremia | Fluid deficit thresholds: 750 mL: Plan completion of procedure OR Stop procedure in patients who are elderly or have comorbidities 1000 mL: Stop procedure |
| Sorbitol 3 percent | Operative: monopolar electrocautery only | Six-carbon sugar Metabolized in the liver to fructose and glucose Elimination half-life: ≥33 min[3] Hypoosmolar | Volume overload Hyponatremia Hypoosmolality Hyperglycemia Peritonitis[4] | ||
| Glycine 1.5 percent | Operative: monopolar electrocautery only | Amino acid Metabolized into serine and ammonia Elimination half-life: ≥40 min[3] Hypoosmolar | Volume overload Hyponatremia Hypoosmolality Hyperammonemia |
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