Components of tyrosine kinase chimeras

Chimeric gene	Origin of promoter and N terminus	Origin of C terminus
RET/PTC1	H4/D10S170	RET
RET/PTC2	Gene which codes for a portion of the regulatory subunit of RI-alpha cAMP-dependent protein kinase A	RET
RET/PTC3	RFG/ELE1	RET
TRK	Tropomyosin gene	NTRK1
TRK1, TRK2	Translocated promoter region (TPR)	NTRK1
TRK3	TRK-fused gene (TFG) which codes for a cytoplasmic protein with the potential for promoting multimer formation	NTRK1

Tyrosine_kinase_chimeras.htm

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