ﺑﺎﺯﮔﺸﺖ ﺑﻪ ﺻﻔﺤﻪ ﻗﺒﻠﯽ
خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Polygenic risk in early-onset oligoarticular juvenile idiopathic arthritis*

Polygenic risk in early-onset oligoarticular juvenile idiopathic arthritis*
Risk factors Number Percent x2 p-value Cumulative odds ratio
DRB1*0801 study (n = 98)
Female sex 89 90.8 14.12 <0.001 4.51
Female + HLA-A2 67 68.4 29.71 <0.001 8.74
Female + HLA-A2, DRB1*0801 21 21.4 17.21 <0.001 63.00
Female + HLA-A2, DRB1*0801, DPB1*0201 10 10.2 8.96 <0.010 119.00
DRB1*1301 study (n = 102)
Female sex 93 91.2 14.44 <0.001 4.55
Female + HLA-A2 74 72.5 7.28 <0.010 5.55
Female + HLA-A2, DRB1*1301 21 20.6 9.78 <0.010 10.50
Female + HLA-A2, DRB1*1301, DPB1*0201 13 12.7 13.21 <0.001 52.00
HLA: human leukocyte antigen, also called major histocompatibility complex (MHC); HLA-A: one of three major types of MHC class I cell surface receptors; HLA-DR and -DP: two types of MHC class II cell surface receptors; B1: beta-1.
* Based on homogenous population of 98 patients studied for DRB1*0801 and of 102 patients studied for DRB1*1301, from Cincinnati/Indianapolis area.
¶ Calculated based on risk of 1.00 for individuals negative for all risk factors.
Graphic 72340 Version 9.0

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