Linkage between lipid infiltration and endothelial injury in atherosclerosis

Oxidized LDL in atherosclerosis. Postulated linkage between oxidized LDL and endothelial injury in the pathogenesis of atherosclerosis. Lipid infiltration may be sufficient to account for fatty streaks (left column), while endothelial injury (right column) may account for progression of the fatty streak to more advanced lesions.