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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Causes of acromegaly

Causes of acromegaly
Primary GH excess
GH-cell adenoma
Mixed GH-cell and PRL-cell adenoma
Mammosomatotroph-cell adenoma
Plurihormonal adenoma
GH-cell carcinoma
Familial syndromes
Multiple endocrine neoplasia type 1 (GH-cell adenoma)
Familial acromegaly
McCune-Albright syndrome (rarely adenoma)
Carney's syndrome
GH excess (ectopic or iatrogenic)
Pancreatic islet-cell tumor
Lymphoma
Iatrogenic
GHRH excess
Central ectopic (<1 percent)
Hypothalamic hamartoma, choristoma, ganglioneuroma
Peripheral ectopic (1 percent)
Bronchial carcinoid, pancreatic islet-cell tumor, small cell lung cancer, adrenal adenoma, medullary thyroid carcinoma, pheochromocytoma
GH: growth hormone; GHRH: growth hormone-releasing hormone; PRL: prolactin.
Adapted from: Melmed S. Acromegaly. N Engl J Med 1990; 322:966.
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