Effect of metabolic disorders on arterial PCO₂

Relationship between arterial plasma [HCO₃] and PaCO₂ in six healthy subjects prior to (normal) and during 14 episodes of steady-state metabolic alkalosis and seven episodes of metabolic acidosis. The solid black line is the mean regression line, and the two thin lines show 95 percent confidence interval. The linear regression is: PaCO₂ = 0.7 [HCO₃] + 20 ± 2 (SEM); L = 0.95.