Markers of fibrogenesis and fibrinolysis

Matrix deposition

Procollagen I peptide

Procollagen III peptide

Type I collagen

Type IV collagen

YKL-40 (chondrex)

Laminin

Hyaluronic acid

Matrix degradation

MMP-2

TIMP-1, -2

Cytokines

TGF-beta

TGF-alpha

PDGF

MMP: matrix metalloproteinase; PDGF: platelet derived growth factor; TGF: transforming growth factor; TIMP: tissue inhibitor of metalloproteinase.

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