Direct immunofluorescence study in ocular cicatricial pemphigoid

The photo shows the presence of linear deposits of IgG at the epithelial basement membrane, an abnormal finding and one that is supportive of the diagnosis of OCP. IgG is also present on the surface epithelium, typical of conjunctivitis from any cause. IgG is also normally found in the substantia propria (connective tissue layer) of human conjunctiva, and is shown to be present in this specimen.