Lymphocytic infiltration in autoimmune primary ovarian insufficiency

Hematoxylin and eosin stains panels A and C; immunoperoxidase stains panels B and D.
(A) Heavy lymphocytic infiltration of the theca (middle).
(B) Same area as A, with the heavy infiltration of lymphocytes highlighted by staining for the leukocyte common antigen.
(C) High power magnification of an early secondary follicle showing three layers of granulosa cells surrounding an unremarkable oocyte.
(D) Same area as C, showing absence of lymphocytic infltration (no leukocyte common antigen positive cells with immunoperoxidase stain).