Alterations in the somatotropic axis in HIV infection

	HIV-infected, no wasting or lipodystrophy	HIV-infected, lipodystrophy	AIDS wasting
GH	Normal	↓	↑
IGF-1	Normal	Normal	↓
IGF-BP-3	Normal	Normal	Normal or ↓

GH: growth hormone; IGF-1: insulin-like growth factor-1; IGF-BP-3: insulin-like growth factor-binding protein-3.

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