Clinical and laboratory features of 1000 consecutive patients with primary myelofibrosis

Feature	Result (percent)
Median age, years (range)	65 (14 to 92)
Males	62
Constitutional symptoms	34
Spleen >10 cm below left costal margin	31
Red cell transfusions required	38
Hemoglobin <10 g/dL	54
White blood cell count >25,000/microL	16
White blood cell count <4000/microL	16
Platelet count <100,000/microL	26
Circulating blasts ≥1 percent	56
JAK2 V617F mutation present	61
MPL mutation present	8
IDH mutation present	4

Data from: Tefferi A, Lasho TL, Jimma T, et al. One thousand patients with primary myelofibrosis: the Mayo Clinic experience. Mayo Clin Proc 2012; 87:25.

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