Skin biopsy from the axilla of a 58-year-old female patient who complained of a chronic, erosive, irritated, intertriginous eruption for years. The histologic examination reveals suprabasilar clefting of the epidermis; full thickness acantholysis with some dyskeratosis near the granular layer; and sparse, perivascular, lymphocytic infiltrate in the papillary dermis with scattered eosinophils. These findings are typical of Hailey-Hailey disease. Direct immunofluorescence was negative.