Syndrome | Characteristics |
Chronic sensorimotor neuropathy | Mild to moderate distal symmetric sensorimotor defects with symmetric pain that begins in the feet and gradually ascends |
Hypertrophic osteoarthropathy | Clubbing of fingers, periostitis of long bones, and occasionally a rheumatoid-like polyarthritis |
Pain, tenderness, and swelling in the knees, wrists, and ankles | |
Paraneoplastic gynecomastia | Breast enlargement, usually presenting with pain |
Paraneoplastic pemphigus | Widespread mucocutaneous lesions involving the lips, conjunctiva, and genitalia |
When severe, desquamation can occur and death may occur from fluid loss, infection, or an associated bronchiolitis obliterans | |
Paraneoplastic Raynaud's phenomenon | Intense vasospasm of digital arterioles leading to pallor, followed by cyanosis and subsequent hyperemia of the fingertips |
Subacute sensory neuronopathy | "Pins and needles" or electric-shock sensations initially affecting an extremity and progresses to involve other extremities, the face, abdomen, and trunk |
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