Version May 2024
| Probable risk factors |
| Total cumulative dose ≥400 units |
| Renal insufficiency |
| Exposure to high partial pressure of oxygen |
| Radiation therapy |
| Age over 40 |
| Cigarette smoking |
| Possible risk factors |
| Concurrent use of cisplatin |
| Concurrent use of granulocyte colony stimulating factor |
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