Efficacy of higher concentrations of beta-lactams against penicillin-resistant pneumococci

More effective	Less effective
Penicillins
Penicillin, amoxicillin Piperacillin	Ticarcillin
Cephalosporins
Second generation Cefuroxime Third generation Cefotaxime Ceftriaxone Cefpodoxime Cefdinir Fourth generation Cefepime Fifth generation Ceftaroline	First generation Cefazolin, cephalexin Second generation Cefaclor Third generation Ceftazidime Cefixime
Carbapenems
Imipenem-cilastatin	Ertapenem

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