Biologically active substances and virulence factors of Bordetella pertussis

Biologically active substances and virulence factors of Bordetella pertussis

Adhesion molecules

Filamentous hemagglutinin*

Pertactin*

Pertussis toxin

Fimbriae

Tracheal colonization factor

Toxins

Tracheal cytotoxin*

Pertussis toxin*

Adenylate cyclase toxin

Dermonecrotic toxin

Lipopolysaccharide

Factors that interfere with phagocytic function

Adenylate cyclase toxin*

Pertussis toxin*

B_pertussis_virulence_facto.htm

* In vitro and in vivo data suggest this factor plays a major role.

Adapted from references [2-7].

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