Allergic disorders |
- Asthma, allergic rhinitis, atopic dermatitis
- Drug hypersensitivity (eg, drug reaction with eosinophilia and systemic symptoms [DRESS], eosinophilia-myalgia syndrome, interstitial nephritis, eosinophilic hepatitis)
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Infectious diseases |
- Helminths (eg, strongyloidiasis, trichinellosis, filariasis, toxocariasis, schistosomiasis, hookworm)
- Ectoparasites (eg, scabies, myiasis)
- Protozoans (eg, isosporiasis, sarcocystis myositis)
- Fungi (eg, coccidioidomycosis, allergic bronchopulmonary aspergillosis, histoplasmosis)
- Viral (eg, HIV)
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Neoplastic disorders |
- Primary hypereosinophilic syndromes (eg, FIP1L1-PDGFRA, -PDGFRB, -FGFR1 rearrangement)
- Acute or chronic eosinophilic leukemia
- Other myeloid neoplasms (eg, chronic myeloid leukemia, systemic mastocytosis)
- Lymphoid malignancies (eg, B cell lymphoma, B or T lymphoblastic leukemia/lymphoma, adult T cell leukemia/lymphoma, cutaneous T cell lymphoma/Sézary syndrome)
- Solid tumors (eg, adenocarcinoma, squamous carcinoma)
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Immunologic disorders |
- Immunodeficiencies (eg, DOCK8 deficiency, hyper-IgE syndrome, Omenn syndrome)
- Autoimmune and idiopathic disorders (eg, sarcoidosis, inflammatory bowel disease, IgG4 disease, other connective tissue disorders)
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Eosinophilic disorders |
- Idiopathic hypereosinophilic syndrome
- Eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome)
- Eosinophilic gastrointestinal disorders
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Miscellaneous |
- Radiation exposure
- Cholesterol emboli
- Hypoadrenalism
- IL-2 therapy
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