Histology of monomorphic epitheliotropic intestinal T cell lymphoma (previously enteropathy-associated T cell lymphoma type 2)

(A) The lymphoma consists of monotonous, medium-sized cells with round nuclei having a stippled chromatin pattern (magnification, 250x). (B) The cells express CD56 (magnification, 250x). The mucosa adjacent to the lymphoma, shows villous atrophy (C; magnification, 100x) and intra-epithelial infiltration by lymphoma cells (D; CD56 staining, magnification, 400x).