In a patient with preeclampsia, the presence of one or more of the following indicates a diagnosis of "preeclampsia with severe features"

Severe blood pressure elevation:

Systolic blood pressure ≥160 mmHg and/or diastolic blood pressure ≥110 mmHg on 2 occasions at least 4 hours apart while the patient is on bedrest; however, antihypertensive therapy generally should be initiated upon confirmation of severe hypertension, in which case criteria for severe blood pressure elevation can be satisfied without waiting until 4 hours have elapsed

Symptoms of central nervous system dysfunction:

New-onset cerebral or visual disturbance, such as:

Photopsia, scotomata, cortical blindness, retinal vasospasm
- and/or
Severe headache (ie, incapacitating, "the worst headache I've ever had") or headache that persists and progresses despite analgesic therapy with acetaminophen and not accounted for by alternative diagnoses

Hepatic abnormality:

Impaired liver function not accounted for by another diagnosis and characterized by serum transaminase concentration >2 times the upper limit of the normal range
- and/or
Severe persistent right upper quadrant or epigastric pain unresponsive to medication and not accounted for by an alternative diagnosis

Thrombocytopenia:

Platelet count <100,000 platelets/microL

Kidney function impairment:

Serum creatinine >1.1 mg/dL [97.2 micromol/L]
- and/or
Doubling of the serum creatinine concentration in the absence of other kidney disease

Pulmonary edema

Reference:

American College of Obstetricians and Gynecologists (ACOG) Practice Bulletin No. 222: Gestational Hypertension and Preeclampsia. Obstet Gynecol 2020; 135:e237.

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خرید پکیج

In a patient with preeclampsia, the presence of one or more of the following indicates a diagnosis of "preeclampsia with severe features"