Common clinical manifestations of radiation-induced fibrosis

Tissues	Manifestations and symptoms
Skin, subcutaneous tissue	Induration, thickening, impaired cosmesis, loss of elasticity, shrinkage, limited joint mobility, lymphedema
Lung	Restrictive pulmonary symptoms, dyspnea, impaired lung function, oxygen dependency
Head and neck	Trismus, mucosal fibrosis, ulcerations, fistula
Gastrointestinal tract	Obstruction, dysphagia, ulceration, fistula, diarrhea, pain
Urinary tract	Ureteral and urethral stenosis, bladder shrinkage, urgency, increased voiding frequency
Female genital tract	Loss of reproductive function, pain, rigidness, shortness and narrowness of vagina, dyspareunia
Muscles	Muscle atrophy, muscle shortening, reduced mobility, decreased strength

Clin_manif_RT_fibrosis.htm

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