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Child-Pugh classification of severity of cirrhosis

Child-Pugh classification of severity of cirrhosis
Parameter Points assigned
1 2 3
Ascites Absent Slight Moderate
Bilirubin <2 mg/dL (<34.2 micromol/L) 2 to 3 mg/dL (34.2 to 51.3 micromol/L) >3 mg/dL (>51.3 micromol/L)
Albumin >3.5 g/dL (35 g/L) 2.8 to 3.5 g/dL (28 to 35 g/L) <2.8 g/dL (<28 g/L)
Prothrombin time (seconds over control) or <4 4 to 6 >6
INR <1.7 1.7 to 2.3 >2.3
Encephalopathy None Grade 1 to 2 Grade 3 to 4
Modified Child-Pugh classification of the severity of liver disease according to the degree of ascites, the serum concentrations of bilirubin and albumin, the prothrombin time, and the degree of encephalopathy. A total Child-Pugh score of 5 to 6 is considered Child-Pugh class A (well-compensated disease), 7 to 9 is class B (significant functional compromise), and 10 to 15 is class C (decompensated disease). These classes correlate with one- and two-year patient survival: class A: 100 and 85%; class B: 80 and 60%; and class C: 45 and 35%.
INR: international normalized ratio.
Graphic 78401 Version 16.0

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