Muscarinic receptors in the lung and the effect of selected anticholinergic medications

Type	Predominant location	Action	Atropine	Ipratropium Oxitropium Tiquizium	Tiotropium
M1	Peribronchial ganglion cells	Bronchoconstriction	Inhibits	Inhibits	Inhibits
		Increased secretion
M2	Postganglionic nerves	Inhibit Ach release	Inhibits	Inhibits	Does not inhibit
		Bronchodilation
M3	Smooth muscle mucous glands	Bronchoconstriction	Inhibits	Inhibits	Inhibits
		Increased secretion

Muscarinic_receptors_in_lun.htm

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