Transmyocardial laser revascularization improves left ventricular myocardial perfusion

The percentage change in myocardial perfusion is calculated as the number of defects at baseline minus the number of defects at follow-up, divided by the number of defects at baseline. Myocardial perfusion improved with transmyocardial laser revascularization (TMLR) but worsened with medical therapy; the percent change in myocardial perfusion differed significantly at each point in time of evaluation (p = 0.001 at three months, p = 0.02 at six months, and p = 0.002 at 12 months). At one year, myocardial perfusion improved by 20 percent in patients undergoing TMLR while is worsened by 27 percent in the medical treatment group.