Adenocarcinoma in small biopsy and cytology

Poorly differentiated non-small cell carcinoma, favor adenocarcinoma.
(A) This core biopsy shows a solid pattern of growth, and morphologically, it lacks any acinar, papillary, or lepidic patterns. The mucin stain was also negative.
(B) The TTF-1 stain is strongly positive.
(C) The p63 stain is very focally positive. The strongly and diffusely positive TTF-1 and only focal p63 staining favor adenocarcinoma. In this case, EGFR mutation was positive.
(D) Cytology from different adenocarcinoma shows large malignant cells with abundant cytoplasm and prominent nuclei growing in an acinar structure.