Version June 2024
| Primary hypothalamic-pituitary dysfunction |
| Immaturity at onset of menarche or perimenopausal decline |
| Intense exercise |
| Eating disorders |
| Stress |
| Idiopathic hypogonadotropic hypogonadism |
| Hyperprolactinemia |
| Lactational amenorrhea |
| Pituitary adenoma or other pituitary tumors |
| Kallman syndrome |
| Tumors, trauma, or radiation of the hypothalamic or pituitary area |
| Sheehan's syndrome |
| Empty sella syndrome |
| Lymphocytic hypophysitis (autoimmune diseases) |
| Other disorders |
| Polycystic ovary syndrome |
| Hyperthyroidism or hypothyroidism |
| Hormone-producing tumors (adrenal, ovarian) |
| Chronic liver or renal disease |
| Cushing's disease |
| Congenital adrenal hyperplasia |
| Premature ovarian failure, which may be autoimmune, genetic, surgical idiopathic, or related to drugs or radiation |
| Turner syndrome |
| Androgen insensitivity syndrome |
| Medications |
| Estrogen-progestin contraceptives |
| Progestins |
| Antidepressant and antipsychotic drugs |
| Corticosteroids |
| Chemotherapeutic agents |
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