"Spontaneous" alveolar rupture |
Alveolar overdistension due to ventilation (eg, excessive tidal volume and/or PEEP) |
Manifestation of primary disease process (eg, ARDS, asthma, ILD, COPD, necrotizing pneumonia) |
Inadvertent alveolar overdistension: - Right main bronchus intubation, severe central airway obstruction, pneumonectomy
- Manual ventilation (bag-mask valve ventilation)
|
Direct injury |
Trauma (penetrating, blunt) |
Resuscitation (mouth-to-mouth, manual ventilation) |
Airway laceration or perforation during intubation attempts |
Biopsy or surgery |
Central line placement |
Thoracentesis |
Failed chest tube placement |
Transbronchial biopsy or bronchial brushing |