Transplant glomerulopathy

Electron micrograph of transplant glomerulopathy reveals marked narrowing of the vascular lumen due to widening of the subendothelial space both by mesangial cell processes (arrow) and by amorphous, electron-lucent material.

Electron micrograph of a normal glomerular capillary loop showing the fenestrated endothelial cell (Endo), the glomerular basement membrane (GBM), and the epithelial cells with its interdigitating foot processes (arrow). The GBM is thin, and no electron-dense deposits are present. Two normal platelets are seen in the capillary lumen.