Version June 2024
| Lipodystrophy |
| Acanthosis nigricans (associated with severe hyperinsulinemia) |
| Muscle hypertrophy, prominent veins |
| Hepatomegaly |
| Fatty liver |
| Cirrhosis |
| Hypertrichosis, hirsutism (occasionally) |
| Cardiomegaly due to hypertrophic cardiomyopathy (occasionally) |
| Developmental delay (occasionally) |
| Metabolic abnormalities |
| Hyperglycemia, but no ketosis |
| Insulin resistance |
| Hypertriglyceridemia |
| Increased metabolic rate |
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