Crude maternal age-specific rates for trisomy 21, Down syndrome, and all chromosome abnormalities

Maternal age, years	Data from live births		Data from 2nd trimester amniocentesis
Maternal age, years	Trisomy 21	All chromosome abnormalities	Trisomy 21	All chromosome abnormalities
33	1/625	1/345	1/416	1/208
34	1/500	1/277	1/333	1/151
35	1/385	1/204	1/250	1/132
36	1/303	1/167	1/192	1/105
37	1/227	1/130	1/149	1/83
38	1/175	1/103	1/115	1/65
39	1/137	1/81	1/89	1/53
40	1/106	1/63	1/69	1/40
41	1/81	1/50	1/53	1/31
42	1/64	1/39	1/41	1/25
43	1/50	1/30	1/31	1/19
44	1/38	1/24	1/25	1/15
45	1/30	1/19	1/19	1/12

Maternal_age_aneuploidy_ris.htm

Data from: Schreinemachers DM, Cross PK, Hook EB. Rates of trisomies 21, 18, 13 and other chromosome abnormalities in about 20,000 prenatal studies compared with estimated rates in live births. Hum Genet 1982; 61:318.

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Crude maternal age-specific rates for trisomy 21, Down syndrome, and all chromosome abnormalities