History and physical examination |
Blood tests |
Complete blood count with differential |
Erythrocyte sedimentation rate |
Serum creatinine concentration |
Liver enzymes, including LDH and alkaline phosphatase |
HIV serology |
Evaluation for supradiaphragmatic disease |
Single posterior/anterior view chest x-ray with adequate abdominal shielding |
Magnetic resonance imaging (if abnormalities seen on chest x-ray) |
Computerized tomography (if MRI not available) |
Evaluation for intraabdominal disease |
Magnetic resonance imaging |
Ultrasound (if MRI not available) |
Computerized tomography (if MRI and ultrasound not available) |
Bone marrow biopsy |
A unilateral bone marrow biopsy should be performed for patients with B symptoms; clinical stage IIB to IV disease; and for patients with anemia, leukopenia, or thrombocytopenia |
Not indicated |
Gallium scan |
PET scan |
Bone scan |
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