Version May 2024
| A thorough physical examination of the newborn should be conducted, including careful measurement of the infant's head circumference, length, weight, and assessment of gestational age. |
| The newborn should be evaluated carefully for neurologic abnormalities, dysmorphic features, splenomegaly, hepatomegaly, and rash or other skin lesions. Any rash, skin lesions, or dysmorphic features should be photographed. If an abnormality is noted, consultation with an appropriate specialist is recommended. |
| Infant serum should be obtained within 2 days of birth and at about age 8 weeks to test for IgM and IgG antibody to WNV. Free testing of samples by CDC can be arranged by contacting state public health laboratories. |
| A newborn hearing screen should be completed by evoked otoacoustic emissions testing or auditory brainstem response testing, either before discharge from the hospital or within 1 month after birth. Infants who fail the initial hearing screen should be referred to an audiologist for further evaluation. |
| Initial examination of the placenta by a pathologist is encouraged. Regardless of whether this is done, the entire placenta, a sample of umbilical cord tissue, and a sample of serum from the umbilical cord should be retained for further evaluation if congenital WNV infection is identified or strongly suspected. A section of the placenta and umbilical cord should be frozen, and the remainder of the placenta should be preserved in formalin; a sample of umbilical cord blood should be centrifuged, and the serum should be refrigerated or frozen. |
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