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PROSTQA model-predicted probabilities of men having functional erections suitable for intercourse two years after brachytherapy for prostate cancer

PROSTQA model-predicted probabilities of men having functional erections suitable for intercourse two years after brachytherapy for prostate cancer
Age, y Race/ethnicity* BMI Predicted functional erections after treatment, percent (95% CI) (by pretreatment sexual HRQOL score)Δ
67 83 100
60 African American <25 78 (48-94) 92 (73-98) 98 (89-99)
25-<35 61 (35-83) 83 (62-94) 94 (83-98)
≥35 28 (7-69) 56 (18-88) 81 (41-96)
White/other <25 54 (33-74) 79 (61-90) 93 (83-97)
25-<35 34 (22-48) 62 (50-73) 85 (75-91)
≥35 11 (3-37) 29 (9-63) 58 (24-86)
65 African American <25 73 (41-91) 89 (67-97) 97 (86-99)
25-<35 54 (28-77) 79 (54-92) 93 (77-98)
≥35 22 (5-62) 48 (14-84) 76 (33-95)
White/other <25 46 (28-66) 73 (55-86) 90 (79-96)
25-<35 27 (18-39) 54 (44-65) 80 (69-88)
≥35 9 (2-30) 23 (6-56) 50 (18-82)
70 African American <25 66 (34-88) 86 (60-96) 95 (81-99)
25-<35 46 (21-73) 73 (45-90) 90 (70-97)
≥35 17 (3-56) 40 (10-80) 69 (25-94)
White/other <25 39 (22-58) 67 (47-82) 87 (72-95)
25-<35 22 (13-33) 47 (34-60) 75 (60-86)
≥35 6 (1-25) 18 (4-50) 42 (13-78)
PROSTQA: Prostate Cancer Outcomes and Satisfaction With Treatment Quality Assessment; BMI: body mass index; HRQOL: health-related quality of life.
* White race/ethnicity included 3 percent of patients of other (non-African American) or unknown races/ethnicities.
¶ Calculated as weight in kilograms divided by height in meters squared.
Δ Specific values of pretreatment sexual functioning (Expanded Prostate Cancer Index Composite scores of 67, 83, and 100; range of 0-100, with a higher score representing better function) are tabulated to represent cohort distribution (25th, 50th, and 75th percentiles of scores among prostatectomy-treated patients) as well as to reflect a clinically relevant set of possible pretreatment sexual functioning. These values correspond to the 45th, 60th, and 85th percentiles among patients treated with brachytherapy. Across all treatment groups, these percentiles correspond to 358 patients (36 percent) with pretreatment sexual HRQOL scores of 67 or less, 441 (45 percent) with scores of 68-99, and 186 (19 percent) with scores of 100.
Reproduced with permission from: Alemozaffar M, Regan MM, Cooperberg MR, et al. Prediction of erectile function following treatment for prostate cancer. JAMA 2011; 306:1205. Copyright © 2011 American Medical Association. All rights reserved.
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