Contraindications to PUVA phototherapy

Absolute

Xeroderma pigmentosum

Lupus erythematosus with photosensitivity or positive Ro antibody

Pregnancy (category C)

Lactation

Relative

Photosensitivity and/photosensitizing medications

History or family history of melanoma

History of nonmelanoma skin cancer and/or extensive solar damage

Previous treatment with ionizing radiation or arsenic

Severe liver, renal, or cardiac disease

Young age

PUVA: psoralen plus ultraviolet A.

References:

Morison WL. Phototherapy and Photochemotherapy of Skin Disease, 3rd ed, Taylor and Francis, New York 2005.
Morison WL. PUVA Photochemotherapy. In: Comprehensive Dermatologic Drug Therapy, 2nd ed, Wolverton SE (Ed), Elsevier, Philadelphia 2007.

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