Version May 2024
| Condition | Distinguishing clinical features |
| Mastoiditis (<2 years) | Ear pain (may manifest as irritability) |
| Postauricular tenderness, erythema, swelling (obliterating postauricular crease), fluctuance, or mass (poorly circumscribed, immobile) | |
| Displacement of the auricle (downward and outward) | |
| Abnormal tympanic membrane | |
| Mastoiditis (>2 years) | Ear pain |
| Postauricular tenderness, erythema, swelling (obliterating postauricular crease), fluctuance, or mass (poorly circumscribed, immobile) | |
| Displacement of the auricle (upward and outward) | |
| Abnormal tympanic membrane | |
| Postauricular lymphadenopathy | Well-circumscribed and freely mobile mass |
| Periauricular cellulitis without otitis externa | Normal tympanic membrane |
| Periauricular cellulitis with otitis externa | Severe pain over the tragus and pinna |
| Auricular perichondritis | Preservation of the postauricular crease |
| Normal tympanic membrane | |
| Mumps | Swelling over the parotid gland rather than the mastoid |
| Normal tympanic membrane | |
| Mastoid tumor | Normal tympanic membrane |
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