- Age >70 years¶
- Obesity (ie, body mass index >35 kg/m2)
- Diabetes mellitus with poor glycemic control (glycated hemoglobin [HbA1c] >7.5% or 58 mmol/mol) despite optimal effort or end-organ damage other than non-proliferative retinopathy
- Irreversible renal dysfunction (eGFR <30 mL/min/1.73 m2)Δ
- Neoplasm (requires individualized assessment of severity, treatment options, and prognosis)
- Infection (requires individualized assessment of severity, treatment options, and prognosis)
- Acute pulmonary embolism (within six to eight weeks)
- Tobacco use (within 6 months)
- Recent past (within 6 months) substance (drug or alcohol) abuse
- Inadequate social support or cognitive-behavioral disability that would prevent compliant care
- Other conditions that increase the risk of perioperative complications or limit tolerance of immunosuppression (eg, peripheral vascular disease that would limit rehabilitation and is not amenable to revascularization, active peptic ulcer disease, cholelithiasis, diverticulosis, advanced hepatic disease)
|