Version June 2024
| Clinical classification |
| Acute hepatocellular injury |
| Injury predominantly to hepatocytes |
| Markedly elevated ALT |
| Mildly elevated alkaline phosphatase |
| Cholestatic injury |
| Injury to bile ducts or the mechanisms affecting flow of bilirubin from serum to bile |
| Disproportionately elevated alkaline phosphatase |
| Mixed injury |
| Features of both acute hepatocellular injury and cholestatic injury |
| Pathogenic classification |
| Intrinsic hepatotoxins |
| Direct chemical reactions |
| Predictable |
| Idiosyncratic reactions |
| Unpredictable |
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